Professor of Chemistry
Education
B.S. Chemistry, St. Louis
M.S. Indiana Univ., Purdue Univ. at Indianapolis (1983);
Ph.D. Physical Chemistry, Texas A&M University (1989);
Postdoc Biophysical Chemistry, Michigan State Univ. (1990)
Contact Information
353 Dow Hall, Dept. Chemistry
Phone: (989) 774-3078 Fax: (989)-774-3883
e-mail: teckl1mm @ cmich.edu
http://www.cst.cmich.edu/users/Teckl1mm/index.htm
Research Fields
Raman and IR spectroscopy of materials
Molecular structure and transformation
Current Research Projects
IIn my research vibrational spectroscopy is used to solve problems dealing with molecular structure. Nearly any type of sample can be analyzed by Raman spectroscopy because of the flexibility of using a focused laser beam as the light source. My current focus is on apatite, a form of calcium phosphate, which is the major constituent of bone and is also found as a natural mineral in rocks. A better understanding of the initial formation and aging of bone and its response to stress is important for improving health. We are making apatite substituted with ions typically found in bone in order to support bone tissue studies. The transformations among crystalline and amorphous forms of calcium phosphates are studied as models of early mineralization. The affect of pressure on bone strength is another area of interest. The nucleation and growth of apatite on silicate surfaces as applied to bone implants are being studied. In another project we are studying the silane hydrolysis process, developing a Raman detection method and studying the kinetics of the process. The materials I study are diverse and have also included proteins containing the heme group (hemoglobin and cytochrome oxidase), inorganic glasses (germanium diselenide doped with metals) and polymers (azoaromatic polyethers). Modern computational modeling of molecular structure and conformation augments my experimental studies.
Selected Publications
Ayorinde Awonusi, Michael D. Morris, Mary M. J. Tecklenburg, “Carbonate Assignment and Calibration in the Raman Spectrum of Apatite” Calcified Tissue International, 2007, 81, 46-52.
E. E. Wilson, Ayorinde Awonusi, M. D.Morris,
D. H. Kohn, M. M. J. Tecklenburg, L. Beck, “Three Structural Roles of Water
in Bone Observed by Solid-State NMR” Biophysical Journal, 2006, 90, 3722-3731.
V.Carmejane, M. D. Morris, M. K. Davis,
L. Stixrude, M. Tecklenburg,
R. M. Rajachar and D. H.
Kohn,
“Bone Chemical Structure Response to Mechanical Stress Studied by High
Pressure Raman Spectroscopy,” Calcified
Tissue International, 2005, 76,
207-213.
Erin Wilson, Ayorinde Awonusi, Micha=
el
Morris, David Kohn, Mary Tecklenburg, Larry Beck, “Highly Ordered
Interstitial Water Observed in Bone by Nuclear Magnetic Resonance,”Journal of Bone and Mineral Research, 2005, 20, 625-634.
Mary M. J.
Tecklenburg, Elisabeth Larsen, Bogdan Lita, Didarul
M. J. Tecklenburg, Derek Kosnak, Atul Bhatnagar and Dillip Mohanty,
"Vibrational Characterization of Azobenzenes, Azoxybenzenes and Azoaromatic and Azoxyaromatic Polyethers," Journal of Raman Spectroscopy
, 1997, 28, 755-763.
Figure below: The inorganic material in bone is
a calcium phosphate (apatite) with a significant level of substituted
carbonate which can be calibrated by changes in the Raman spectrum.
