Distinguished Research Professor/Scientist Scientific Director, The National Dendrimer & Nanotechnology Center Central Michigan University
Education
B.A. Chemistry, University of Michigan
Ph.D. Physical-Organic Chemistry, Michigan State University
Contact Information
Dow Science Complex
Phone: (989) 774-7207 Fax: (989)-774-3883
e-mail: tomal1d@cmich.edu
Research Fields
Design and synthesis of novel dendrimers/dendritic polymers. Atom mimicry, nano-periodic properties and relationships. Synthetic nano-chemistry. Structural hybridization of well defined nanoscale building blocks to synthesize novel nano-devices
Selected Publications
“Unique Steric and Geometry Induced Stoichiometries Observed in the Divergent Synthesis of Poly(ester-acrylate/amine) (PEA) Dendrimers,” D.R. Swanson, B. Huang, H.G. Abdelhady, D.A. Tomalia, New J. Chem., 31, 1368-1378 (2007).
“Dendrimers – An Enabling Synthetic Science to Controlled Organic Nanostructures,” D.A. Tomalia, S.A. Henderson, M.S. Diallo, Chapter 24 in Handbook of Nanoscience, Engineering and Technology, Second Edition, edited by W.A. Goddard III, D.W. Brenner, S.E. Lyshevski, G.J. Irafrate, CRC Press, Taylor and Francis, Boca Raton, 24.1-24.47 (2007).
“Dendrimers as Multi-Purpose Nanodevices for Oncology Drug Delivery and Diagnostic Imaging,” D.A. Tomalia, L.A. Reyna, S. Svenson, Biochemical Society Transactions, 35(1), 61-67, (2007).
“AFM Analysis of C60 and a Poly(amido amine) Dendrimer-C60 Nanoconjugate,” M. Chai, A.W. Jensen, H.G. Abdelhady, D.A. Tomalia, J. of Nanoscience and Nanotechnology, 7 (4-5) 1401-1405 (2007).
“Poly(ether) Dendrons Possessing Phosphine Focal Points for Stabilization and Reduced Quenching of Luminescent Quantum Dots,” B. Huang, D.A. Tomalia, Inorganica Chimica Acta, 359, 1961-1966 (2006).
“Structure of Gold Nanoparticles Suspended in Water Studied by X-ray Diffraction and Computer Simulations,” V. Petkov, Y. Peng, G. Williams, B. Huang, D. Tomalia, Y. Ren, Phys. Rev. B, 72, 195402-1 (2005).
“Dendrons/Dendrimers. The Convergence of Quantized Dendritic Building Blocks/Architectures for Applications in Nanotechnology,” D.A. Tomalia, Chemistry Today, 23(6), 41-45, November/December (2005).
Selected Publications
“Polyacrylamide gel electrophoresis separation and detection of polyamidoamine dendrimers possessing various cores and terminal groups,” A. Sharma, A. Desai, R. Ali, D.A. Tomalia, Journal of Chromatography A, 1081, 238-244 (2005).
“Preparation of Fullerene-Shell Dendrimer-Core Nanoconjugates,” A.W. Jensen, B.S. Maru, X. Zhang, D.K. Mohanty, B.D. Fahlman, D.R. Swanson, D.A. Tomalia, Nano Letters, 5(6), 1171-1173 (2005).
“Dendrimeric Supramolecular and Supramacromolecular Assemblies,” D.A. Tomalia, Chapter 7 in Supramolecular Polymers, Second Edition, CRC Press Taylor & Francis, Boca Raton, FL, (2005).
“Birth of a New Macromolecular Architecture: Dendrimers as Quantized Building Blocks for Nanoscale Synthetic Polymer Chemistry,” D.A. Tomalia, Prog. Polym. Sci., 30, 294-324 (2005).
“Dendronization of Gold and CdSe/CdS (Core-Shell) Quantum Dots with Tomalia Type, Thiol Core, Funtionalized Poly(amidoamine) (PAMAM) Dendrons, B. Huang, D.A. Tomalia, J. of Luminescence, 111, 215-223 (2005).
“Designed Dendrimer Syntheses By Self-Assembly of Single Site, ssDNA Functionalized Dendrons,” C.R. DeMattei, B. Huang, D.A. Tomalia, NanoLetters, 4(5), 771-777 (2004).
“Structure Control within Poly(amidoamine) Dendrimers: Size, Shape and Regio-chemical Mimicry of Globular Proteins”, D.A. Tomalia, B. Huang, D.R. Swanson, H.M. Brothers II, J.W. Klimash, Tetrahedron, 59, 3799-3813 (2003).
“Partial Shell Filled Core-Shell Tecto(dendrimers): A Strategy to Surface Differentiated Nano-Clefts and Cusps,” D.A. Tomalia, H.M. Brothers II, L.T. Piehler, H. Dupont Durst, D.R. Swanson, Proc. Nat. Acad. Of Sciences, 99(8), 5081-5087 (2002).
Dendrimers and Other Dendritic Polymers, a monograph edited by D.A. Tomalia and J.M.J. Fréchet, J. Wiley & Sons Ltd., Chichester (2001).
“Dendrimers—Silver Complexes and Nanocomposites as Antimicrobial Agents,” L. Balogh, D.R. Swanson, D.A. Tomalia, G.L. Hagnauer, A.T. McManus, NanoLetters, 1(1), 18-21 (2001).
“Core-Shell Tecto(dendrimers). I. Synthesis and Characterization of Saturated Shell Models,” S. Uppuluri, D.R. Swanson, L.T. Piehler, J. Li, G.L. Hagnauer, D.A. Tomalia, Adv. Mater., 12(11), 796-800 (2000).
“Inhibition of Viral Adhesion and Infection by Sialic-Acid-Conjugated Dendritic Polymers,” J.D. Reuter, A. Myc, M.M. Hayes, Z. Gan, R. Roy, D. Qin, R. Yin, L.T. Piehler, R. Esfand, D.A. Tomalia, J.R. Baker, Jr., Bioconjugate Chem., 10(2), 271-278 (1999).
“Poly(Amidoamine) Dendrimer-Templated Nanocomposites. 1. Synthesis of Zerovalent Copper Nanoclusters," L. Balogh, D.A. Tomalia, J. Am. Chem. Soc., 120, 7355-7356 (1998).
“Architectural Copolymers: Rod-Shaped, Cylindrical Dendrimers,” R. Yin, Y. Zhu, D.A. Tomalia, J. Am. Chem. Soc., 120, 2678-2679 (1998).
“A Contemporary Survey of Covalent Connectivity and Complexity. The Divergent Synthesis of Poly(thioether) Dendrimers. Amplified, Genealogically Directed Synthesis Leading to the de Gennes Dense Packed State,” M.K. Lothian-Tomalia, D.M. Hedstrand, D.A. Tomalia, A.B. Padias, H.K. Hall, Jr., Tetrahedron, 53(45), 15495-15513 (1997).
“Dendrimer Molecules,” D.A. Tomalia, Scientific American, 272(5), 62-6 (1995).
“Starburst/Cascade Dendrimers: Fundamental Building Blocks for a New Nanoscopic Chemistry Set,” D.A. Tomalia, Advanced Materials, 6, 7/8, 529 (1994).
“Dendrimer-Based Metal Chelates: A New Class of Magnetic Resonance Imaging Contrast Agents,” E.C. Wiener, M.W. Brechbiel, H. Brothers, R.L. Magin, O.A. Gansow, D.A. Tomalia and P.C. Lauterbur, Magnetic Resonance in Medicine, 31(1), 1-8 (1994).
"Molecular Recognition and Chemistry in Restricted Reaction Spaces. Photophysics and Photoinduced Electron Transfer on the Surfaces of Micelles, Dendrimers and DNA," N.J. Turro, J.K. Barton and D.A. Tomalia, Acc. Chem. Res., 24(11), 332-40 (1991).
“STARBURST® Dendrimers V. Molecular Shape Control,” A.M. Naylor, W.A. Goddard III, G.E. Kiefer, D.A. Tomalia, J. Am. Chem. Soc., 111, 2339-41 (1989).